Unsurprisingly, the 49ers lead the all-time series between these two teams. Surprisingly, they only lead 36-29 — a ...

Kyler Murray and the Arizona Cardinals (1-3) have not been consistent and are banged up on the offensive line, but they have ...

ARIZONA -- The Arizona Cardinals and San Francisco 49ers have released their final injury report of the Week 5 practice slate ...

What to look for from the top 49ers and Cardinals players and how to watch the game as they face off on Sunday, week 5.

San Francisco will have to wear their red jerseys at home during record heat, despite Kyle Shanahan's request to wear white.

Budda Baker will make his 100th career NFL start for the Arizona Cardinals on Sunday amid rumors he might be dealt before the ...

The 49ers are already seeking relief for players and fans ahead of Sunday’s game at Levi’s Stadium, where the kickoff ...

San Francisco 49ers general manager John Lynch spoke on Friday about the team's contingency plan in case Fred Warner is out ...

Outside of one glorious game against the Rams, the first quarter of the season has not been kind to the Arizona Cardinals. At ...

The Arizona Cardinals got a significant injury boost Friday, as head coach Jonathan Gannon announced that tight end Trey ...

The Arizona Cardinals (1-3) are 7.5-point underdogs in a road NFC West matchup against the San Francisco 49ers (2-2) on ...

Preview the Week 5 matchup between the San Francisco 49ers and Arizona Cardinals with predictions, odds, over/under, spread, ...