What to look for from the top 49ers and Cardinals players and how to watch the game as they face off on Sunday, week 5.

Head coach Kyle Shanahan told reporters Friday that the team put in a request to the NFL to switch from their usual red home ...

PM ET on FOX, oddsmakers have installed player prop betting options on Jordan Mason. Mason and the San Francisco 49ers (2-2) ...

The Arizona Cardinals and San Francisco 49ers have released their final injury report of the Week 5 practice slate. Both ...

Budda Baker will make his 100th career NFL start for the Arizona Cardinals on Sunday amid rumors he might be dealt before the ...

The 49ers are already seeking relief for players and fans ahead of Sunday’s game at Levi’s Stadium, where the kickoff ...

San Francisco 49ers general manager John Lynch spoke on Friday about the team's contingency plan in case Fred Warner is out ...

The Arizona Cardinals got a significant injury boost Friday, as head coach Jonathan Gannon announced that tight end Trey ...

Preview the Week 5 matchup between the San Francisco 49ers and Arizona Cardinals with predictions, odds, over/under, spread, ...

Arizona Cardinals HC Jonathan Gannon gave some key injury updates in his Friday press conference. "Happy Friday. Trey McBride ...

Outside of one glorious game against the Rams, the first quarter of the season has not been kind to the Arizona Cardinals. At ...

The Arizona Cardinals (1-3) are 7.5-point underdogs in a road NFC West matchup against the San Francisco 49ers (2-2) on ...