Weight-loss drugs like Ozempic and Wegovy have become household names in recent years. But here's why they may not work for everyone.

James Corden has been known to struggle with his weight, and was often known as the 'fat funny element' on TV and film. Corden, who moved to the US and began his role has an evening entertainment chat show host, lifted the lid on his recent lifestyle transformation, and revealed the issue his Ozempic use posed for him.

Ozempic, one of the semaglutide drugs that helped stars like Elon Musk, Whoopi Goldberg, and Oprah lose weight, is said to suppress hunger. But James Corden said on his Sirius XM show, This Life of Mine, that Ozempic led him to a realization, "Nothing about my eating has anything to do with being hungry."

During a recent episode of his "This Life of Mine" podcast, James Corden opened up about trying the medication for weight-loss and explained why it "didn't really work" for him.

"I tried Ozempic, and it won’t be surprising to you when you look at me now, that it didn’t really work," the British TV star said (as transcribed by People). "I tried it for

Former late-night host James Corden has revealed he tried Ozempic for weight loss but found it ineffective. "I tried Ozempic," Corden, who recently stated he was led on by Lily Allan, recently said on his podcast This Life of Mine.